When the earth is threatened by alien invaders, a ragtag group of monsters is assembled to save the planet. B.O.B. (Seth Rogen), a gelatinous blob; Dr. Cockroach, Ph.D (Hugh Laurie), an insect-headed genius; the Missing Link (Will Arnett), a macho half-ape, half-fish; Susan "Ginormica" Murphy (Reese Witherspoon), a 50-foot tall woman; and Insectosaurus, a 350-foot grub must learn how to work together and coordinate their wacky powers in order to prevent the alien invastion. Directed by Rob Letterman and Conrad Vernon. With Paul Rudd, Kiefer Sutherland, Rainn Wilson and Stephen Colbert. Categories: Comedy, Fantasy, Animation, Adventure, Family. Year: 2009.

Hugh Laurie, Seth Rogen and Stephen Colbert in Monsters vs. Aliens

Hugh Laurie in Monsters vs. Aliens

Stephen Colbert in Monsters vs. Aliens

Reese Witherspoon in Monsters vs. Aliens

Monsters vs. Aliens

Rainn Wilson in Monsters vs. Aliens

Kiefer Sutherland and Stephen Colbert in Monsters vs. Aliens

Monsters vs. Aliens

Hugh Laurie and Seth Rogen in Monsters vs. Aliens

Reese Witherspoon in Monsters vs. Aliens

Hugh Laurie, Seth Rogen, Kiefer Sutherland and Will Arnett in Monsters vs. Aliens

Reese Witherspoon in Monsters vs. Aliens
Seth Rogen also appeared in Anchorman: The Legend of Ron Burgundy, Donnie Darko, The 40 Year Old Virgin, You, Me and Dupree, Superbad, Drillbit Taylor, Knocked Up, The Spiderwick Chronicles, Horton Hears a Who!, Kung Fu Panda, Pineapple Express, Zack and Miri Make a Porno, Fanboys, Observe and Report, Funny People, and Paper Heart.
Reese Witherspoon also appeared in Legally Blonde, Pleasantville, American Psycho, Walk the Line, Sweet Home Alabama, Rendition, Penelope, Little Nicky, Legally Blonde 2: Red, White & Blonde, Four Christmases, Just Like Heaven, and The Importance of Being Earnest.
Hugh Laurie also appeared in Street Kings and Cousin Bette.
Paul Rudd also appeared in Wet Hot American Summer, Anchorman: The Legend of Ron Burgundy, The Cider House Rules, The 40 Year Old Virgin, The Shape of Things, Clueless, Walk Hard: The Dewey Cox Story, Reno 911!: Miami, Knocked Up, Forgetting Sarah Marshall, Romeo & Juliet, Role Models, I Love You, Man, Year One, and Over Her Dead Body.
Kiefer Sutherland also appeared in Dark City, Flatliners, The Lost Boys, Taking Lives, A Few Good Men, A Time to Kill, Eye for an Eye, Woman Wanted, The Three Musketeers, The Cowboy Way, Desert Saints, The Vanishing, Stand by Me, Mirrors, and The Sentinel.
Rainn Wilson also appeared in My Super Ex-Girlfriend, The Last Mimzy, Juno, The Rocker, Transformers: Revenge of the Fallen, and Sahara.
Will Arnett also appeared in Monster-in-Law, Ratatouille, The Brothers Solomon, Blades of Glory, Semi-Pro, Horton Hears a Who!, Hot Rod, G-Force, When in Rome, and Brief Interviews with Hideous Men.
Stephen Colbert also appeared in Bewitched.
Rob Letterman also appeared in Shark Tale.
Conrad Vernon also appeared in Shrek 2.